49Up was on CBC Newsworld. The link goes to the wikipedia that explains the premise of the documentaries. All the films are amazing to watch. But this one with the subjects at now at 49, you can see the arc of their lives revealed. Now we are introduced to the grandkids, and some of the subject can look ahead to retirement. They also can recount some of the effects of being involved with the series has had on their lives.
Rodger Ebert calls this series one of his top ten of all time. He interviewed Michael Apted, the director, here